Founded in 2012, Lightstone Ventures has offices in Menlo Park, California, and other locations. It has invested in companies such as Earlens Corporation, Bold Penguin, and Locana, with a focus on pharmaceutical and medical device sectors. The fund typically invests in startups that are 4-5 years old and participates in rounds with 5-6 other investors. Lightstone Ventures has a higher exit rate compared to other organizations and has been active in 2-6 investment rounds annually. The fund has raised a total of $472 million across three funds, with its latest fund, Fund II, raising $250 million.