Applied Genetics Technologies Corporation

Company

Investment-firm

Last deal

$10M

Amount

Post-IPO Equity

Stage

12.07.2022

Date

3

all rounds

$195.05M

Total amount

Financing round

General

About Company
AGTC is a biotech company that develops gene therapies for rare diseases.

Industry

Sector :

Subsector :

Also Known As

AGTC

founded date

01.01.1999

Number of employees

Company Type

For Profit

Last funding type

Post-IPO Equity

IPO status

Private

Description

AGTC uses cutting-edge techniques to develop treatments for patients with diseases caused by broken genes, using gene therapy to replace those broken genes with normal functional genes, leading to a better quality of life for patients worldwide. Their initial focus is on ophthalmology, with clinical trials in X-linked retinitis pigmentosa, achromatopsia, and X-linked retinoschisis, and preclinical programs in optogenetics, adrenoleukodystrophy, and other ophthalmology and otology indications. AGTC employs a highly targeted approach to selecting and designing its product candidates, choosing to develop therapies for indications with high unmet medical need, clinical feasibility, and commercial potential, and has a significant intellectual property portfolio and extensive expertise in the design of gene therapy products.
Contacts

Contact Email

Phone number

Website URL

Social url

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M&A Details
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Acquired by

Syncona Partners LLP

announced date

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Financials

Funding Rounds
8
3

Number of Funding Rounds

$195.05M

Money Raised

Their latest funding was raised on 12.07.2022. Their latest round Post-IPO Equity

Date 
Funding Round 
Investors 
Money Raised 
Lead 
12.07.2022
$10M
28.01.2021
$74.5M
06.02.2020
$32.5M
Investments
1
Date 
name 
Lead 
type 
Raised 
29.03.2001
Yes
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Investors
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Number of investors

Investor 
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Arnie Oronsky

Arnie Oronsky

Dr. Arnie Oronsky has been with InterWest's life sciences team since 1994. He is a board member of Amplimmune, Applied Genetic Technologies Corporation (AGTC), Arcion, Drais Pharmaceuticals, Dynavax Technologies (DVAX), Integrated Diagnostics, MacroGenics, RadioRX, TESARO and USDS. As a Ph.D. in immunology and senior lecturer at the Department of Medicine at Johns Hopkins Medical School, Arnie brings a deep understanding of medical research to finding and investing in successful life sciences companies. Prior to joining InterWest, Arnie was vice president for discovery research of the Lederle Laboratories division of American Cyanamid Company where he directed the research for new drugs. Arnie received a Ph.D. in immunology from Columbia University and has published more than 125 articles in scientific journals.

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People

Founders
6
Nicholas Muzyczka
Nicholas Muzyczka

Nicholas Muzyczka

Nicholas Muzyczka is a Co-Founder at Lacerta Therapeutics.

current job

Applied Genetics Technologies Corporation
Applied Genetics Technologies Corporation

organization founded

2

Nicholas Muzyczka

R. Jude Samulski
R. Jude Samulski

R. Jude Samulski

Richard Samulski, Ph.D. serves as the President of Chatham Therapeutics LLC. Samulski has been Scientific Co-Founder of Asklepios Biopharmaceutical, Inc. since 2003 and served as its Chief Executive Officer. In 1993, Samulski co-founded an AAV-based gene therapy company Merlin. He also co-founded Applied Genetic Technologies Corporation in 1999. He also serves as a gene therapy consultant to the FDA. Through the UNC gene therapy center, Samulski has produced within an academic setting an FDA approved AAV clinical vector used to treat children with the neurological disorder of Canavan's disease. He serves as Professor of Pharmacology of The University of North Carolina. Samulski served at AAV for 25 years. Samulski has been Director of the University of North Carolina Gene Therapy Center for eight years. He serves as a Member of Scientific Advisory Board of Ceregene, Inc. He served at AAV biology as a Member of the scientific advisory board of Avigen, a new AAV research company. Samulski has over 20 patents filed or issued in the area of AAV vectors. Samulski served as a Member of the Recombinant DNA Advisory Committee (RAC), a committee tasked with assisting the FDA with approving or disapproving gene therapy clinical trials in the United States. Samulski is a recipient of the President's Distinguished Research Award from the University of Pittsburgh. He completed Post-Doctoral training at Princeton. Samulski's graduate work (1978-82) demonstrated the first use of AAV as a viral vector and culminated in the first US patent involving non-AAV genes inserted into AAV. Samulski received his PhD in Medical Microbiology and Immunology from the University of Florida and his research focuses on the study of the dependent parvovirus adeno-associated virus (AAV)

current job

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Asklepios BioPharmaceutical

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R. Jude Samulski

William Hauswirth
William Hauswirth

William Hauswirth

Hauswirth received his B.S. in Chemistry from Stanford University and his Ph.D in Physical Chemistry from Oregon State University. After an NIH Fellowship in the Biochemistry Department at Johns Hopkins University, he joined that department as an Assistant Professor. In 1976, he joined the faculty of Molecular Genetics and in 1985 the Ophthalmology faculty at the University of Florida. While at UF. Hauswirth is, in part, responsible for determining the mechanism of replication of adeno-associated virus (AAV) DNA and the discovery of mitochondrial DNA heteroplasmy in mammals. More recently he collaborated on the first successful rescue of a dominant genetic disease in animals (ribozyme treatment in a Retinitis Pigmentosa model in rats) and the first restoration of vision for a recessive retinal disease (congenitally blind Briard dogs). His current interests involve the delivery and testing of potentially therapeutic genes for Retinitis Pigmentos.

current job

Applied Genetics Technologies Corporation
Applied Genetics Technologies Corporation

organization founded

1

William Hauswirth

Barry Byrne
Barry Byrne

Barry Byrne

Barry Byrne joined University of Florida as Professor in 1997.Byrne is a Pediatric Cardiologist clinician and Associate chair of the Congenital Heart Center at UF. He is a professor in pediatrics and molecular genetics and is currently the director of the University of Florida Powell Gene Therapy Center. His research is aimed to help those affected by genetic muscular diseases and he is currently the PI on multiple clinical trials for this effort. His primary involvement lies with disorders such as Pompe, Barth, muscular dystrophy, and the associated cardiomyopathy of these diseases. Byrne obtained his B.S. in Chemistry from Denison University in Ohio, his M.D. and Ph.D. from the University of Illinois, and completed his residency and fellowship training at Johns Hopkins University in Maryland. He was an Assistant Professor at Hopkins after completing his training before coming to the University of Florida in 1997.

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Employee Profiles
13
Mark S.Shearman

Mark S.Shearman

Chief Scientific Officer

Stephen Potter

Stephen Potter

Chief Business Officer

Larry Bullock

Larry Bullock

Chief Financial Officer

Sue Washer

Sue Washer

Founder ,President & CEO

R. Jude Samulski

R. Jude Samulski

Founder

William Hauswirth

William Hauswirth

Founder

Barry Byrne

Barry Byrne

Founder

Scott Koenig

Scott Koenig

Chairman of the Board of Directors

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