Joseph R. Hyde III

Mr. Hyde, in conjunction with Dr. Wills’ appointment as our Executive Chairman effective March 2, 2015, was appointed as the Board’s Lead Director and currently serves as a member of the Compensation Committee and the Nominating and Corporate Governance Committee. Previously, he served as Chairman of our Board of Directors from November 2000 through February 2015. Since 1989, Mr. Hyde has been the sole stockholder and President of Pittco Holdings, Inc., a private institutional investment company. Since 1996, when Mr. Hyde made a substantial contribution to support the research of one of the company’s founders, Mr. Hyde has been instrumental in helping direct and finance GTx and is our largest stockholder. Mr. Hyde was the Chairman of the Board of Directors of AutoZone, Inc. from 1986 to 1997 and the Chief Executive Officer of AutoZone from 1986 to 1996. From March 2005 to June 2007, Mr. Hyde served as the non-executive chairman of the Board of Directors of AutoZone, Inc., and continues to serve as a member of the Board. He was also Chairman and Chief Executive Officer of Malone & Hyde, Inc., AutoZone’s former parent company, from 1972 until 1988. Mr. Hyde also served as a director of FedEx Corporation from 1977 to 2011. As our largest stockholder and with a long history of serving as both Chairman and Chief Executive Officer of a large publicly-traded company and a member of the board of directors of other public companies, Mr. Hyde has continued to serve as a principal architect of our public company governance structure, and is an influential advisor to senior management on all matters of strategic importance.