Founded in 1997, Skyline Ventures focuses on investing in healthcare companies that develop small molecule and protein therapeutics, medical devices, diagnostics, and technologies for drug discovery and life science research. The firm's team, consisting of professionals with MD or PhD degrees and hands-on operating experience in start-ups, offers value as board members and shareholders. They prioritize data-driven decision-making and look for proof of principle in a company's products. Skyline Ventures typically leads or co-leads a company's first or second institutional venture round and targets investments of $15-35 million per portfolio company over its lifetime. With approximately $800 million under management, the firm has a strong track record in the healthcare sector and has invested in companies such as NovaSys, Calibra Medical, and Satiety.