Founded in 2002 in Harrisburg, Pennsylvania, Life Sciences Greenhouse of Pennsylvania focuses on investing in local research universities, colleges, medical centers, and economic development sectors. The fund prefers startups that are 4-5 years old and operates primarily in the United States. It typically invests between $5-10 million in each deal and has a higher rate of exit commitments compared to other companies. Some of its notable portfolio startups include NanoHorizons, Immunomic Therapeutics, and Novasentis. The fund also collaborates with other investors such as Roche Venture Fund, Berwind Private Equity, and Ben Franklin Technology Partners of Northeastern Pennsylvania.