Founded in 1994 and headquartered in Durham, North Carolina, Pappas Ventures invests in companies in the biotechnology, specialty pharmaceuticals, drug delivery, medical devices, and related sectors. They have made over 85 investments in the United States and Canada, with a particular interest in startups developing treatments for human diseases. Notable portfolio companies include Allievex, Reneo Pharmaceuticals, Ribometrix, Mirum Pharmaceuticals, Milestone Pharmaceuticals, CuraSen Therapeutics, 4D Molecular Therapies, Amplyx Pharmaceuticals, and OrphoMed. Pappas Ventures brings experience, creativity, and passion to their partnerships, working to bring promising technologies from concept to commerce in the life sciences sector.