The firm, established in 1999 and headquartered in Waltham, Massachusetts, invests in companies at different stages of development, from seed-stage to later-stage, within sectors such as B2C, media, B2B, commercial services, big data, health tech, TMT, manufacturing, and technology. Millennium Ventures either revitalizes acquired organizations or creates new ventures based on emerging trends and dynamic themes, such as the need for real-time decision-making data in an uncertain economy and the growth of optical science-based products in healthcare devices and defense.