Last deal

$50M

Amount

Post-IPO Debt

Stage

13.11.2023

Date

3

all rounds

$265.1M

Total amount

date founded

Financing round

General

About Company
Acumen is developing a drug to treat Alzheimer's disease.

Industry

Sector :

Subsector :

founded date

01.01.1996

founders

Number of employees

Company Type

For Profit

Last funding type

Post-IPO Debt

IPO status

Private

Description

Acumen's lead drug candidate, ACU193, is a monoclonal antibody that selectively targets amyloid-beta oligomers. The company is currently conducting a Phase 1 clinical trial of ACU193 to evaluate its safety and tolerability and explore its pharmacokinetics and target engagement in early Alzheimer's disease patients. The trial is enrolling patients with mild cognitive impairment and mild dementia due to Alzheimer's disease, and Phase 1 data are expected by year end 2022. Acumen's focus on the biology of toxic soluble amyloid-beta oligomers has led to decades of research, and the company is now poised to realize the therapeutic potential of Aβo targeted drugs.
Contacts

Contact Email

Phone number

Social url

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Their latest funding was raised on 13.11.2023. Their latest investor K2 HealthVentures. Their latest round Post-IPO Debt

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People

Founders
1

Grant Krafft

Dr. Grant Krafft is a co-founder of Acumen and currently serves as Chief Scientific Adviser and Chairman of the Board of Directors.Dr. Krafft was formally Acumen’s Chief Scientific Officer. Prior to Acumen, Dr. Krafft was Research Professor of Molecular Pharmacology and Biological Chemistry at Northwestern University Medical School, where he and his colleagues discovered Amyloid-beta Derived Dementing Ligands (ADDLs). Dr. Krafft also served as Director of Research Development for the ENH Research Institute, a Northwestern University Medical School affiliate. Previously, Dr. Krafft was Chief Technical Officer of Tibotec-Virco, a HIV therapeutics and pharmacogenomics company, and a Volwiler Research Fellow at Abbott Laboratories in its Diagnostics and Pharmaceutical Products Divisions. Dr. Krafft holds a B.S. in Chemistry from Valparaiso University, and a Ph.D. in Organic Chemistry from the University of Illinois, Urbana-Champaign, and was a NIH post-doctoral fellow at the University of Wisconsin, Madison.

organization founded

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Grant Krafft

Employee Profiles
6
Daniel J. O'Connell

Daniel J. O'Connell

Director, President & CEO

Russell Barton

Chief Operating Officer

Eric Siemers

Chief Medical Officer

Matt Zuga

Matt Zuga

Chief Financial Officer & Chief Business Officer

Daniel O'Connell

President & Chief Executive Officer

Activity

Recent News
6
News Timeline

The graph reveals the ratio (%) of positive news articles in a chosen time range

week