Crinetics Pharmaceuticals

Company

Investment-firm

Last deal

$350M

Amount

Post-IPO Equity

Stage

28.02.2024

Date

3

all rounds

$1.15B

Total amount

Financing round

General

About Company
Crinetics discovers, develops, and sells therapeutics for rare endocrine diseases and tumors.

Industry

Sector :

Subsector :

Keywords :

founded date

01.01.2008

Number of employees

Company Type

For Profit

Last funding type

Post-IPO Equity

IPO status

Private

Description

The company's product candidates include paltusotine for the treatment of acromegaly and neuroendocrine tumors, CRN04777 for congenital hyperinsulinism, and CRN04894 for diseases of excess adrenocorticotrophic hormone, including Cushing's Disease, congenital adrenal hyperplasia, and Ectopic ACTH Syndrome. Crinetics uses objective hormonal biomarker endpoints for preclinical and clinical studies to reduce both the risk and cost to achieve meaningful clinical data. The company is seeking motivated partners to help advance their programs to become commercially successful products and is committed to developing much-needed therapies for people with rare endocrine diseases.
Contacts

Phone number

Social url

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3

Number of Funding Rounds

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Money Raised

Their latest funding was raised on 28.02.2024. Their latest investor GordonMD Global Investments. Their latest round Post-IPO Equity

Date 
Funding Round 
Investors 
Money Raised 
Lead 
28.02.2024
10
$350M
13.09.2023
$350M
12.04.2022
$125M
Investments
2
Date 
name 
Lead 
type 
Raised 
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People

Founders
3
Stephen F. Betz
Stephen F. Betz

Stephen F. Betz

Stephen F. Betz (Vice President, Biology) is a Founder of Crinetics Pharmaceuticals. He earned his Ph.D. in Chemistry from the University of North Carolina at Chapel Hill where he studied protein structure and stability. He pursued postdoctoral studies in the laboratory of William DeGrado at the DuPont Merck Pharmaceutical Company where he focused on protein engineering and de novo design. He moved to pharmaceutical discovery in the Research NMR Group at Abbott Laboratories, working on protein structure, structure-guided drug design, assay development, and compound screening in several different therapeutic areas. Subsequently, he led laboratory efforts at GeneFormatics, a biotechnology company founded on protein function annotation and characterization. Most recently, he was Director of Endocrinology and Metabolism at Neurocrine Biosciences working on the discovery and development of GnRH receptor antagonists and nonpeptide modulators of other endocrine targets.

current job

Crinetics Pharmaceuticals
Crinetics Pharmaceuticals

Stephen F. Betz

Yun-Fei Zhu
Yun-Fei Zhu

Yun-Fei Zhu

Yun-Fei (Frank) Zhu (Vice President, Chemistry) is a Founder of Crinetics Pharmaceuticals. He received his Ph.D. in Organic Chemistry from Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences in China, and pursued his postdoctoral studies in the laboratory of Professor Murray Goodman in Department of Chemistry, University of California, San Diego. He joined Neurocrine Biosciences in 1997 where he led chemistry efforts on discovery of nonpeptide GnRH antagonists. He was most recently a Director of Chemistry in the Endocrinology and Metabolism group. His research has involved discovery of small molecule inhibitors of several neuropeptide receptors including CRFR2, MCH receptor, and GnRH-R for the treatment of a range of endocrine diseases.

current job

Radionetics Oncology
Radionetics Oncology

organization founded

1

Yun-Fei Zhu

Scott Struthers
Scott Struthers

Scott Struthers

R. Scott Struthers (CEO & Chief Scientific Officer) is a Founder of Crinetics Pharmaceuticals. Dr. Struthers received his Ph.D. in Physiology and Pharmacology from the University of California, San Diego, under the supervision of Professor Wylie Vale. Following his degree, he led contract research efforts at Biosym Technologies developing and applying computational tools for drug discovery. He then cofounded ScienceMedia Inc. to develop eLearning solutions for the life sciences and higher education markets. From 1998 to 2008 he held a series of positions at Neurocrine Biosciences, most recently as Senior Director and Head, Endocrinology and Metabolism. There he initiated and led the company’s efforts to discover and develop orally active, nonpeptide GnRH antagonists. This resulted in a first-in-class compound, elagolix, that has demonstrated good safety and efficacy in over 40 clinical trials totaling more than 3000 patients including a 6-month, 872 patient recently completed Phase III study. In 2008, he founded Crinetics Pharmaceuticals to focus on discovery and development of drugs targeting neuropeptide receptors for the treatment of endocrine related diseases and cancers. Dr. Struthers is an author of more than 75 scientific publications.

current job

Radionetics Oncology
Radionetics Oncology

organization founded

1

Scott Struthers

Employee Profiles
18
Dana Pizzuti

Dana Pizzuti

Chief Development Officer

Chris Robillard

Chief Business Officer

Jeff Knight

Jeff Knight

COO

Brian Russell

Director, business development

Dana Jennings

Senior manager, contracts and procurement

Elizabeth Bautista

Principal scientist

Dana Rilatos

Senior manager, contracts and procurement

Joe Pontillo

Associate director, chemistry

Activity

Recent News
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