amcure
Company

Last deal

$2.1M
Local Amount - EUR 1.8M

Amount

Grant

Stage

31.08.2017

Date

3

all rounds

$15.1M

Total amount

General

About Company
amcure is a clinical-stage company developing peptide-based compounds for the treatment of highly metastatic forms of squamous cancer.

Industry

Sector :

Subsector :

Keywords :

founded date

01.01.2011

Number of employees

Company Type

For Profit

Last funding type

Grant

IPO status

Private

Description

amcure is a spin-off from the Karlsruhe Institute of Technology, supported by a grant from the German Federal Ministry of Education and Research. The company's compounds include an advanced development candidate, AMC303, which uses peptide-based compounds that target one highly specific co-receptor, CD44v6, blocking several relevant oncological pathways involved in tumor growth, angiogenesis and the development and regression of metastases. Their approach differs fundamentally from known experimental or approved compounds in this area, as they target CD44v6, combining the advantages of receptor specificity and broadband inhibition. Their first-in-class CD44v6-inhibitor AMC303 entered clinical development in solid tumors in Q4 2016, showing significant efficacy in relevant POC animal studies against highly metastatic epithelial cancers, enabling doctors to advance in the treatment of pancreatic cancer, head cancer, neck cancer, gastric cancer, colorectal cancer, breast cancer and lung cancer.