Founded in 2002, Piedmont Angel Network focuses on investing in early-stage companies in the life sciences, technology, software solutions, and advanced materials fields. With three funds raised and investments in 33 companies, the fund typically invests between $250,000 and $350,000. While it prefers to invest in the Piedmont Triad region of North Carolina, it has also made investments across North Carolina, South Carolina, and Virginia. Some of its successful portfolio startups include Guerrilla RF, Akros Medical, and AvidXchange. The fund has a higher exit rate compared to other organizations and is known for its active member participation throughout the investment process.