The firm, founded in 2012 and headquartered in Palo Alto, California, seeks to invest in various sectors, including enterprise, mobile, consumer, internet of things, health tech, and fintech. Its principals and advisors have backgrounds in operations research, data science, and game theory. Venture/Science is a growth stage investment firm that is best known for its use of quantitative decision principles such as stochastic finance and multi-factor analysis in venture capital. The firm's main investment themes include storage, networking, security, social, mobile, apps, gaming, cloud, big data, hardware, wearables, VR, drone tech, ecommerce, payments, marketplaces, life sciences, and biotechnology.