Founded in 2003 and headquartered in Portland, Maine, Maine Angels has invested over $25 million in more than 50 companies. They focus on both pre-revenue and post-revenue companies, with a majority of their investments in Maine and New England. Notable portfolio startups include ezCater, Cognition Therapeutics, and SQZ Biotech. The firm typically invests in rounds with 1-2 partakers, and their average investment size ranges from $100,000 to $1 million. Maine Angels is also associated with Dirigo Angel Fund I, an early-stage venture capital fund that will make 12 to 13 investments in Maine over 2 to 3 years.