Founded in 1998 and headquartered in Waltham, Massachusetts, Confluent Surgical develops a range of biomaterial products, including sealants, adhesion barriers, and hemostatic agents, to address complications during and after surgery. Their flagship product, DuraSeal Dural Sealant, is used for watertight closure during cranial surgeries. Acquired by US Surgical in 2006, Confluent Surgical focuses on developing products based on their proprietary technology of in-situ polymerized hydrogels and associated delivery systems.