Based in Grand Rapids, Michigan and Westlake, Ohio, Hopen Life Science Ventures invests in early to mid-stage life sciences companies, particularly in medical devices, diagnostics, therapeutics, healthcare information technology, and drug discovery enabling technology sectors. They prefer to invest in the Midwest of the United States and offer funding, developmental and managerial experience, and industry network support to their portfolio companies. Some of their notable investments include Cirius Therapeutics, Delphinus Medical Technologies, and Sierra Oncology.