Last deal

$60M

Amount

Corporate Round

Stage

08.11.2021

Date

3

all rounds

$210.13M

Total amount

date founded

Financing round

General

About Company
Gyroscope is a clinical-stage gene therapy company focused on developing therapies for eye diseases.

Industry

Sector :

Subsector :

Also Known As

Gyroscope

founded date

01.01.2016

Number of employees

Company Type

For Profit

Last funding type

Corporate Round

IPO status

Private

Description

The company's lead investigational gene therapy, GT005, is designed to restore balance to an overactive complement system by increasing the production of the Complement Factor I protein. GT005 is currently being evaluated in Phase II clinical trials for the treatment of geographic atrophy secondary to age-related macular degeneration (AMD), a leading cause of blindness. Gyroscope was co-founded in 2016 and acquired by Novartis in February 2022. The company aims to preserve sight and fight the devastating impact of blindness by combining discovery, research, drug development, manufacturing, and surgical delivery capabilities.
Contacts
Legal Names

Legal name

Gyroscope Therapeutics Limited
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M&A Details
1

Transaction name

Acquired by

Novartis

announced date

22.12.2021

price

$1.5B

Financials

Funding Rounds
4
3

Number of Funding Rounds

$210.13M

Money Raised

Their latest funding was raised on 08.11.2021. Their latest investor Syncona Partners LLP. Their latest round Corporate Round

Date 
Funding Round 
Investors 
Money Raised 
Lead 
08.11.2021
1
$60M
26.03.2021
7
$89.19M
Local Amount - GBP 123M
03.09.2019
2
$60.94M
Local Amount - GBP 50.4M
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Subsector

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Co-Investors
Investors
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Number of lead investors

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Number of investors

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Robert Tansley

Robert Tansley

Robert Tansley has been with CIC since January 2014 and heads up the team that focuses on healthcare and associated technologies. After seven years working in hospital medicine, Robert joined the pharma industry in 1996 working in development and regulatory roles at Sanofi, the MHRA and Roche where he led the clinical team for the regulatory approval of Valcyte®. Robert then joined the Cambridge-based company Arakis and worked as Medical Director until its £106 million sale to Sosei Inc. Since that acquisition, he has been involved in a number of start-up companies, including founding the malaria-focused company Treague and being founding CEO of the University of Copenhagen spin-out Avilex Pharma. In addition he was part of the founding management team of KalVista which is developing the first plasma kallikrein inhibitor for diabetic macular edema in collaboration with its scientific co-founders from Harvard Medical School. Robert qualified in medicine from University College London. He is a member of the Royal College of Obstetricians & Gynaecologists and the Faculty of Pharmaceutical Medicine and has an MBA from London Business School and an M.Phil in Biostatistics from the University of Cambridge.

current job

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Subsector

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Location

Baltimore, MD, USA

count Of Investments

281

count Of Exists

42
Acquisitions
1
Acquiree Name 
Date 
Price 
Acquisition Name 
Orbit Biomedical acquired by Gyroscope Therapeutics

Orbit Biomedical acquired by Gyroscope Therapeutics

acquirer

Gyroscope Therapeutics
Gyroscope Therapeutics

date

11.04.2019
Orbit Biomedical

Orbit Biomedical

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Sector

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Subsector

Biotechnology

Keywords

Biotechnology, Health Care, Medical Device

Location

Ambler, PA 19002, USA

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1

People

Founders
3
David Kavanagh
David Kavanagh

David Kavanagh

David Kavanagh is the Professor of Complement Therapeutics at the National Renal Complement Therapeutics Centre (NRCTC). The NRCTC is a combined clinical, diagnostic and treatment centre for the complement mediated diseases: atypical haemolytic uraemic syndrome (aHUS) and C3 glomerulopathy. All patients in England treated with eculizumab for these diseases are managed through the NRCTC. His University research group has been at the forefront of defining the role of complement in renal disease and is fully integrated with the NRCTC to provide rapid translational benefits to patients. David moved to Newcastle to start his own lab in 2008 with a Wellcome Trust Fellowship following a Kidney Research UK Fellowship at the University of Edinburgh. He was previously a Fellow at Washington University School of Medicine, St. Louis. He graduated in Medicine and Immunology from the University of Glasgow in 1998 and obtained his PhD from Newcastle University in 2006. For his work defining the role of complement in aHUS, he was awarded the Renal Association’s Young Investigator (Raine) award. Additionally, he runs a glomerulonephritis and vasculitis clinic at Freeman hospital. He is chairman of the aHUS rare disease working group, an executive committee member of Complement UK

current job

Gyroscope Therapeutics
Gyroscope Therapeutics

organization founded

1

David Kavanagh

Peter Lachmann
Peter Lachmann

Peter Lachmann

Sir Peter Lachmann is emeritus Sheila Joan Smith Professor of Immunology at the University of Cambridge, a fellow of Christ’s College, Cambridge and honorary fellow of Trinity College, Cambridge and of Imperial College. He was knighted for service to medical science in 2002. He has won numerous international accolades including a Gold Medal from the European Complement Network in 1997, the Medicine and Europe Senior Prize, Academie des Sciences de la Santé in 2003. His primary research interest now is the downregulation of the complement alternative pathway as a treatment for age related macular degeneration. he has previously worked on many aspects of complement biology; on microbial subversion of the innate immune response; on the immunology of measles, on systemic lupus erythematosus and on insect sting allergies.

current job

Gyroscope Therapeutics
Gyroscope Therapeutics

organization founded

1

Peter Lachmann

Andrew Lotery
Andrew Lotery

Andrew Lotery

Andrew is Professor of Ophthalmology at the University of Southampton, Director of the Clinical Neurosciences Research Group and an Honorary Consultant Ophthalmologist at University Hospital Southampton NHS Foundation Trust. Andrew’s scientific research is within the genetic associations of eye disease, with his clinical research focussed on AMD. He has one of the largest patient data-sets and clinical sample banks in the UK. He is the chief investigator on Roche’s Phase 3 trial of lampalizumab for dry AMD and was a co-investigator on the first clinical gene therapy trial for choroideremia. Andrew is an Observer at the Gyroscope Board of Directors.

current job

Gyroscope Therapeutics
Gyroscope Therapeutics

organization founded

1

Andrew Lotery

Employee Profiles
10
Arman Nadershahi

Arman Nadershahi

Senior Director, Associate General Counsel

Charlotte Arnold

Charlotte Arnold

Vice President, Corporate Affairs

Chris Clevenger

Vp, global medical affairs

Reagan Callahan

Senior people partner

Khurem Farooq

Khurem Farooq

Chief Executive Officer

David Kavanagh

David Kavanagh

Professor of Nephrology, Newcastle, Academic Founder

Peter Lachmann

Peter Lachmann

Academic Founder

Andrew Lotery

Andrew Lotery

Professor of Ophthalmology, University of Southampton, Academic Founder

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