Japanese scientists created a drug capable of stimulating the growth of new teeth
Researchers at the Kitano Medical Institute are actively involved in the development of drugs aimed at promoting tooth regeneration
In Osaka, the Kitano Medical Institute’s Japanese scientists have initiated the development of a groundbreaking drug designed to induce the growth of a third set of teeth. Initially, the drug aims to benefit individuals who have a genetic-related absence of a complete set of molars, a condition known as adentia, affecting approximately 1% of the global population.
The root cause of adentia has been identified as the USAG-1 protein, which inhibits tooth growth. However, through meticulous research, the scientists managed to create an antibody that effectively neutralises this protein, as demonstrated in successful tests conducted on mice.
The potential impact of growing a third set of teeth is significant, offering an alternative to dentures or implants for those unable to undergo conventional dental treatments due to severe caries or other reasons. The researchers are optimistic that in the years to come, a tooth-restoring medication will be made accessible.
Anticipated clinical trials for the drug are scheduled for 2024, with the researchers expecting its availability to the public by 2030.
